Synthetic Organic Chemistry & Catalysis • University of Oxford

Martin Smith Research Group

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Publications

Niels Münster, Nicholas Parker, Lucy van Dijk, Robert S. Paton & Martin D. Smith.
Angew. Chem. Int. Ed. 2017, 56, 9468-9472.
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  • Neutral Iodotriazole Foldamers as Tetradentate Halogen Bonding Anion Receptors
A. Borrisov, J. Y. C. Lim, K. E. Christensen, A. L. Thompson, M. D. Smith & P. D. Beer
Chem. Commun. 2017, 53, 2483.
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J. D. Jolliffe, R. J. Armstrong & Martin D. Smith.
Nature Chem. 2017, 9, 558.
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Shuyu Chu, Niels Munster, Tudor Balan & Martin D. Smith.
Angew. Chem. Int. Ed. 2016, 55, 14306-14309.
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Emily Kiss, Craig D. Campbell, Russell W. Driver, John D. Jolliffe, Rosemary Lang, Tetiana Sergeieva, Sergiy Okovytyy, Robert S. Paton & Martin D. Smith.
Angew. Chem. Int. Ed. 2016, 55, 13813-13817.
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Benjamin F. Rahemtulla, Hugh F. Clark & Martin D. Smith.
Angew. Chem. Int. Ed. 2016, 55, 13180-13183.
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Russell W. Driver, Timothy D. W. Claridge, Steve Scheiner & Martin D. Smith.
Chem. Eur. J. 2016, 22, 16513-16521.
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N-Benzyl quininium chloride
; K. Badiola & M. D. Smith, Enyclopedia of Organic Reagents, 2016, Eds. P. L. Fuchs, J. W. Bode, A. B. Charette & T. Rovis, John Wiley & Sons, London.
  • Cation-Directed Enantioselective Functionalization of Pyrroles (S. V. Ley 70th Birthday Special Edition)
R. J. Armstrong, M. D'Ascenzio & Martin D. Smith.
Synett. 2016, 18, 5372.
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A. D. Lamb, P. D. Davey, R. W. Driver, A. L. Thompson & Martin D. Smith.
Org. Lett. 2016, 27, 6
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Krishna Sharma, Jamie R. Wolstenhulme, Phillip P. Painter, David Yeo, Francisca Grande-Carmona, Craig P. Johnston, Dean J. Tantillo & Martin D. Smith.
J. Am. Chem. Soc. 2015,137, 13414-13424.
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Craig P. Johnston, Abhishek Kothari, Tetiana Sergeieva, Sergiy I. Okovytyy, Kelvin E. Jackson, Robert S. Paton & Martin D. Smith.
Nature Chem. 2015, 7, 171.
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P. P. Mangione, S. Deroo, S. Ellmerich, V. Belotti, S. Kolstoe, S. P. Wood, C. V. Robinson, M. D. Smith, G. A. Tennant, R. L. Broadbridge, C. E. Council,  J. R. Thurston, V. A. Steadman, A. K. Vong, C. J. Swain. M. B. Pepys & G. W. Taylor.
Open Biology 2015, 5, 150105.
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S. Chu, S. Wallace & Martin D. Smith.
Angew. Chem. Int. Ed. 2014, 53, 13826-13829.
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R. J. Armstrong & Martin D. Smith.
Angew. Chem. Int. Ed. 2014, 53, 12822-12825.
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P. C. Knipe & Martin D. Smith.
Org. Biomol. Chem. 2014, 12, 5094-5097.
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C. P. Johnston & M. D. Smith.
Angew. Chem. Int. Ed. 2014, 53, 3315-3317.
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J. R. Wolstenhulme, A. Cavell, M. Gedicak, R. W. Driver & Martin D. Smith.
Chem. Commun. 2014, 50, 13585-13588.
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P. C. Knipe, M. Gredicak, A. Cernijenko, R. S. Paton & Martin D. Smith.
Chem. Eur. J. 2014, 20, 3005-3009.
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M. Li, P. A. Woods & Martin D. Smith.
Chem. Sci. 2013, 4, 2907.
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C. R. Jones, P. K. Baruah, A. L. Thompson, S. Scheiner & Martin D. Smith
J. Am. Chem. Soc. 2012, 134, 12064.

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E. E. Maciver, P. C. Knipe, A. Cridland, A. L. Thompson & Martin D. Smith
Chem. Sci. 2012, 3, 537-440.

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E. E. Maciver, S. Thompson & Martin. D Smith
Angew. Chem. Int. Ed. 2009, 48, 9979

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C. R. Jones, G. D. Pantos, A. J. Morrison & Martin D. Smith
Angew. Chem. Int. Ed. 2009, 48, 9979

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C. R. Jones, M. K. N. Qureshi, F. R. Truscott, S.-Te D. Hsu, A. J. Morrison & Martin D. Smith
Angew. Chem. Int. Ed. 2008, 47, 7099

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Older Publications

DOI Asymmetric Electrocyclic Reactions, S. Thompson, A. G. Coyne, P. C. Knipe & M. D. Smith, Chem. Soc. Rev. 2011, 40, 4217-4231.
DOI Trapping Of Palindromic Ligands Within Native Transthyretin Prevents Amyloid Formation, S. E. Kolstoe, P. P. Mangione, V. Bellotti, G. W. Taylor, G. A. Tennent, S. Deroo, A. J. Morrison, A. J. A. Cobb, A. G. Coyne, M. G. McCammon, T. D. Warner, J. Mitchell, R. Gill, M. D. Smith, S. V. Ley, C. V. Robinson, S. P. Wood & M. B. Pepys, Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 20483-20488.
DOI Glycosylation Catalyzed by a Chiral Brønsted Acid, D. J. Cox, M. D Smith & A. J. Fairbanks, Org. Lett. 2010, 12, 1452-1455.
DOI Favorskii Rearrangment Of A Highly Functionalized Meso-Dihaloketone, P. M. Tomlin, D. J. Davies & M. D Smith, Tetrahedron: Asymm. Prof G. W. J. Fleet Special Issue, 2009, 20, 961-969.
DOI Bend-Ribbon Forming γ-Peptides, A. Kothari, M. K. N. Qureshi, E. Beck & M. D. Smith, Chem. Commun. 2007, 2814-2816.
DOI The Total Synthesis of Five Thapsigargins – Guaianolide Natural Products Exhibiting Sub-Nanomolar SERCA Inhibition, S. P. Andrews, M. Ball, F. Wierschem, E. Cleator, S. F. Oliver, K. Högenauer, O. Simic, A. Antonello, U. Hünger, M. D. Smith & S. V. Ley, Chem. Eur. J. 2007, 13, 5688-5712.
DOI Total Synthesis of Thapsigargin, a Potent SERCA Pump Inhibitor, M. Ball, S. P. Andrews, F. Wierschem, E. Cleator, M. D. Smith & S. V. Ley, Org. Lett. 2007, 9, 663-666.
DOI Parallel Sheet Structure In Cyclopropane γ-Peptides Stabilized by C-H···O Hydrogen Bonds, M. K. N. Qureshi & M. D. Smith, Chem. Commun. 2006, 5006-5008.
DOI Targeting C-Reactive Protein For Treatment of Human Cardiovascular Disease, M. B. Pepys, G. M. Hirschfield, G. A. Tennent, J. R. Gallimore, V. Bellotti, P. N. Hawkins, R. M. Myers, M. D. Smith, A. Polara, A. Cobb, S. V. Ley, A. Aquilina, C. V. Robinson, I. Sharif, G. Gray, C. A. Sabin, M. C. Jenvey, S. E. Kolstoe, D. Thompson & S. P Wood, Nature 2006, 440, 1217-1222.
DOI Synthesis of Two Subpicomolar Sarco/Endoplasmatic Reticulum Ca2+-ATPase (SERCA) Inhibitors Designed by an Analysis of the Binding Site of Thapsigargin, H. Søhoel, T. Liljefors, S. V. Ley, S. F. Oliver, A. Antonello, M. D. Smith, C. E. Olsen, J. T. Isaacs, & S. B. Christensen, J. Med. Chem. 2005, 48, 7005-7011.
DOI Copper and Palladium-Containing Perovskites: Catalysts For The Ullmann And Sonogashira Reactions, S. Lohmann, S. P. Andrews, B. Burke, M. D. Smith, S. V. Ley, J. P. Attfield & H. Tanaka, Synlett, 2005, 1291-1295 [Erratum Synlett, 2005, 1490].
DOI Total Synthesis of Antascomicin B, D. E. A. Brittain, C. M. Griffiths-Jones, M. R. Linder, M. D. Smith, C. McCusker, J. S. Barlow, R. Akiyama, K. Yasuda & S. V. Ley, Angew Chem. Int. Ed. 2005, 44, 2732-2737.
DOI Homogeneous or Heterogeneous? Palladium Containing Perovskites in the Suzuki Reaction, S. P. Andrews, A. F. J. F. Stepan, S. V. Ley & M. D. Smith, Adv. Synth. Catal. 2005, 347, 647-654.
DOI Helix-Forming Tetrahydrofuran Amino Acids, T. D. W. Claridge, G. H. Grant, D. D. Long, B. Odell, C. M. Baker, A. A. Edwards, G. E. Tranter, G. W. J. Fleet & M. D. Smith, J. Org. Chem. 2005, 70, 2082-2090.
DOI Synthesis of the Thapsigargins, S. V. Ley, A. Antonello, E. P. Balskus, D. T. Booth, S. B. Christensen, E. Cleator, H. Gold, K. Högenauer, U. Hünger, R. M. Myers, S. F. Oliver, O. Simic, M. D. Smith, H. Søhoel & A. J. A. Woolford, Proc. Natl. Acad. Sci. U. S. A. 2004, 101, 12073-12078.
DOI A Route to the Thapsigargins from (S)- Carvone Providing a Substrate Controlled Total Synthesis of Trilobolide, Nortrilobolide and Thapsivillosin F, S. F. Oliver, K. Högenauer, O. Simic, A. Antonello, M. D. Smith & S. V Ley, Angew. Chem. Int. Ed. 2003, 42, 5996-6000.
DOI Palladium-Containing Perovskites: Recoverable And Reuseable Catalysts For Suzuki Couplings, M. D. Smith, A. F. J. F. Stepan, C. Ramarao, P. E. Brennan & S. V. Ley, Chem. Commun. 2003, 2652-2653.
DOI Bend Ribbon-Forming Tetrahydrofuran Amino Acids, M. D. Smith, T. D. W. Claridge, M. S. P. Sansom & G. W. J. Fleet, Org. Biomol. Chem. 2003, 1, 3647-3655.
DOI Synthesis Of All Diastereomeric Methyl 2, 5-Anhydro-3-Deoxy-Hexonates: Precursors To C-2-Deoxynucleosides And THF Templated γ- and δ-Amino Acids, M. P. Watterson, A. A. Edwards, J. A. Leach, M. D. Smith, O. Ichihara & G. W. J. Fleet, Tetrahedron Lett. 2003, 44, 5853-5857.
DOI Complex Tetrahydrofurans From Carbohydrate Lactones: THF Amino Acids as Unnatural Biopolymer Building Blocks, D. D. Long, M. D. Smith, A. Martin, D. G. Watkin, M. Müller & G. W. J. Fleet, J. Chem. Soc., Perkin Trans. 1 2002, 1982-1998.
DOI Polyurea Encapsulated Palladium Acetate: a Robust and Recyclable Catalyst for use in Conventional and Supercritical Media, S. V. Ley, C. Ramarao, R. S. Gordon, A. B. Holmes, A. J. Morrison, I. F. McConvey, I. M. Shirley, S. C. Smith & M. D. Smith, Chem. Commun. 2002, 1134-1135.
DOI Tetra-N-Propylammonium Perruthenate: A Case Study in Catalyst Recovery and Re-use with Tetraalkylammonium Salts, S. V. Ley, C. Ramarao & M. D. Smith – Chem. Commun. 2001, 2278-2279.
Arsenic Compounds in Science of Synthesis: Houben-Weyl Methods of Molecular Transformations, M. D. Smith - Vol. 4, pp 1-41, Eds. S. V. Ley & I. Fleming, Georg Thieme Verlag, Stuttgart, 2001.
DOI Carbopeptoids: Peptides and Diketopiperazines Incorporating the Anomeric Centre of Mannopyranose, D. D. Long, R. J. Tennant-Eyles, J. C. Estevez, M. R. Wormald, M. D. Smith & G. W. J. Fleet, J. Chem. Soc., Perkin Trans. 1 2001, 807-813.
DOI Tetrahydrofuran Amino Acids: Versatile Building Blocks for Unnatural Biopolymers, D. E. A. Brittain, M. P. Watterson, T. D. W. Claridge, M. D. Smith and G. W. J. Fleet, J. Chem. Soc., Perkin Trans. 1 2000, 3655-3665.
DOI An Approach to Combinatorial Library Generation of Galactofuranose Mimics in the Search for Inhibition of Mycobacterial Cell Wall Biosynthesis: Synthesis of a Peptidomimetic of Uridine 5’-Diphosphogalactofuranose, R. E. Lee, M. D. Smith, L. Pickering & G. W. J. Fleet, Tetrahedron Lett. 1999, 40, 8689-8692.
DOI Designing Secondary Structures: Carbohydrate Derived Dipeptide Isosteres, M. D. Smith & G. W. J. Fleet, J. Pept. Sci. 1999, 5, 425-441.
DOI 3-Azidotetrahydrofuran-2-carboxylates: Monomers for a Family of Five Ring Templated β-amino acid Foldamers, M. P. Watterson, L. Pickering, M. D. Smith, S. H. Hudson, P. R. Marsh, J. E. Mordaunt, D. J. Watkin, C. J. Newman & G. W. J. Fleet, Tetrahedron: Asymm. 1999, 10, 1855-1859.
DOI Tetrahydrofuran α-Azido Esters: Precursors of Anomeric α-Amino Acid Monomers via Radical Bromination, M. D. Smith, D. D. Long, A. Martin, N. Campbell, Y. Blériot & G. W. J. Fleet, Synlett 1999, 1151-1153.
DOI An Octameric Carbopeptoid; Secondary Structure in Octameric and Tetrameric 5-Aminomethyl-Tetrahydrofuran-2-carboxylates, T. D. W. Claridge, D. D. Long, N. L. Hungerford, R. T. Aplin, M. D. Smith, D. G. Marquess & G. W. J. Fleet, Tetrahedron Lett. 1999, 40, 2199-2202.
DOI From Sequencamers to Foldamers?  Secondary Structure in Tetrameric Furanose Carbopeptoids From cis- and trans-5-Aminomethyl-Tetrahydrofuran-2-carboxylates, D. D. Long, N. L. Hungerford, M. D. Smith, D. E. A. Brittain, D. G. Marquess, T. D. W. Claridge & G. W. J. Fleet, Tetrahedron Lett. 1999, 40, 2195-2198.
DOI Absence of Secondary Structure in a Carbopeptoid Tetramer of a trans-5-Aminomethyl-Tetrahydrofuran-2-carboxylate, M. D. Smith, D. D. Long, T. D. W. Claridge, D. G. Marquess, A. Martin & G. W. J. Fleet, Tetrahedron Lett. 1999, 40, 2191-2194.
DOI A Solid Phase Approach to Oligomers of Carbohydrate Amino Acids: Secondary Structure in a Trimeric Carbopeptoid, D. D. Long, M. D. Smith, D. G. Marquess, T. D. W. Claridge & G. W. J. Fleet, Tetrahedron Lett. 1998, 39, 9293-9296.
DOI Secondary Structure in Oligomers of Carbohydrate Amino-Acids, M. D. Smith, T. D. W. Claridge, G. E. Tranter, M. S. P. Sansom & G. W. J. Fleet, Chem. Commun. 1998, 2041-2042.
DOI Synthesis of Oligomers of Tetrahydrofuran Amino-Acids: Furanose Carbopeptoids, M. D. Smith, D. D. Long, T. D. W. Claridge, D. G. Marquess & G. W. J. Fleet, Chem. Commun. 1998, 2039-2040.
DOI Sugar Mimics From Sugar Lactones, G W. J. Fleet, J. C. Estevez, M. D. Smith, Y. Blériot, C. de la Fuente, T. M. Krülle, G. S. Besra, P. J. Brennan, R. J. Nash, L. N. Johnson, N. G. Oikonomakos & W. Stalmans, Pure Appl. Chem. 1998, 70, 279-284.
DOI Inhibition of UDP-Gal Mutase and Mycobacterial Galactan Biosynthesis by Pyrrolidine Analogues of Galactofuranose, R. E. Lee, M. D. Smith, R. J. Nash, R. C. Griffiths, M. McNeil, W. Yan, G. S. Besra, P. J. Brennan & G. W. J. Fleet, Tetrahedron Lett. 1997, 38, 6733-6736.
DOI Mimics of L-Rhamnose: Analogues of Rhamnopyranose Containing a Constituent α-Amino Acid at the Anomeric Position. A Pyranose Analogue of Hydantocidin, J. C. Estevez, M. D. Smith, M. R. Wormald, G. S. Besra, P. J. Brennan & G. W. J. Fleet, Tetrahedron: Asymm. 1996, 7, 391-394.

DOI Mimics of L-Rhamnose: Anomeric Spirohydantoins and Diketopiperazines- Approaches to Novel N-Linked Glycopeptides of Rhamnofuranose, J. C. Estevez, M. D. Smith, A. L. Lane, S. Crook, D. J. Watkin, G. S. Besra, P.J. Brennan & G. W. J. Fleet, Tetrahedron: Asymm. 1996, 7, 387-390.