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Research: Total Synthesis of Complex Natural Products

We are interested in the synthesis of nitrogen-containing natural products as they comprise an important class of structurally complex pharmacologically active agents.

We are investigating general routes to natural products such as those pictured herein via cascade cyclization routes. These complex scaffolds offer wide-ranging opportunities for the develpoment of new synthetic methods to enable practical assembly of such complex polycyclic cores.

Targets currently under investigation within the group include:

nat prod targets

Foldamers -- Total Synthesis -- Catalysis